Topical Publications

Topical Bases

Stability studies conducted using our cream and gel bases provide solutions to common stability issues faced by pharmacists in establishing appropriate Beyond Use Dates (BUDs).

• Prospective, Randomized, Double-Blind, Placebo-Controlled Study on Efficacy of Copaiba Oil in Silicone-Based Gel to Reduce Scar Formation
  Waibel, J. Lupatini, R. Patel, H. Cull, E. Sidhu, R. (2021).
  Dermatology and Therapy
• Minoxidil 2%-5.5% and 6%-15% in Foamil
  Lupatini, R. Sidhu, R. Patel, H. Bichar, K. (2021).
  Stability Evaluation of Minoxidil in FOAMIL Foam Base with Bracketing Study Design
  IJPC Vol 25 No. 3
• Feasibility Study of Asthma Cream
  Kuang, A. (2020)
  International Journal of Pharmaceutical Compounding.
  IJPC. Vol 24.No 2.
• Randomised controlled trial evaluating the short-term analgesic effect of topical diclofenac on chronic Achilles tendon pain: a pilot study
  Bussin, E. R. Cairns, B. Bovard, J. Scott, A. (2017).
  BMJ Open
  
• Evaluation and Comparison of Wound Healing Properties of an Ointment (AlpaWash) Containing Brazilian Micronized Propolis and Peucedanum ostruthium Leaf Extract in Skin Ulcer in Rats
  Nani, M. Leone, A. Bom, V. P. Buszinski, A. F. De Souza R. O. Pinheiro V. A. Danopoulos, P. Swikidisa, R. Marquele-Oliveira, F. Frade, M. A. C. Berretta, A. A. Nogueira, R. J. L. (2018).
  International Journal of Pharmaceutical Compounding.
  IJPC. Vol 22. No 2.
• Development and Validation of HPLC Assay Method for Stability Testing of a High-Potency Diclofenac Sodium Gel
  LTarbox, T. Lyness, G. Hellinghausen, G. Eklov, A.S. Watts, A. (2016).
  AAPS 2016 National Biotechnology Conference.
  
• Evaluation of the antibacterial activity of Green Propolis extract and Meadowsweet extract against Staphylococcus aureus bacteria: importance in wound care compounding preparations.
  Lupatini Nogueira, R.J. Danopoulos, P. Swikidisa, R. Alves Pinheiro, V. (2016).
  International Journal of Pharmaceutical Compounding.
  IJPC. Vol 20.No 4.
• Antimicrobial Activity of Copaíba (Copaifera officinalis) and Pracaxi (Pentaclethra macrobola) Oils against Staphylococcus Aureus: Importance in Compounding for Wound Care
  Guimarães, A. L. A. Cunha, E. A. Matias, F. O. Garcia, P. G. Danopoulos, P. Swikidisa, R. Pinheiro, V. A. Nogueira, R.J.L. (2016).
  International Journal of Pharmaceutical Compounding.
  IJPC. Vol 20. No 1.
• Progesterone Cream 10% in HRT Cream and in PLO Transdermal Cream
  BasuSarkar, A. Kandimalla, A. Dudley, R. (2013).
  Chemical Stability of Progesterone in Compounded Topical Preparations using PLO Transdermal Cream™ and HRT Cream™ Base over a 90-Day Period at Two Controlled Temperatures.
  J Steroids Horm Sci. Vol 4. No 2.
• Estradiol Cream 0.025% - Estrone Cream 0.025% - Estriol Cream 0.2%
  BasuSarkar, A. Kandimalla, A. Dudley, R. (2012).
  Ninety day Chemical Stability of Compounded Estradiol, Estrone and Estriol combination and Beyond Use Date.
  JPSI. Vol 1. No 5.
• Hydrocortisone Cream 2%
  BasuSarkar, A. Dudley, R. Melethil, R. Speidel, J. Markandakumar Bhatt. G. (2011)
  Chemical stability of Hydrocortisone in topical preparation in proprietary VersaPro cream base.
  Innovations. Vol 2. No 3.
• Naproxen 5% in PLO Gel Mediflow – Naproxen 20% in PLO Gel Mediflow 30
  BasuSarkar, A. Sekar, C. Durga Paruchiri, R. (2011).
  Stability Studies on Naproxen Cream.
  Int. J. App. Sci. Tech. Vol 1. No 5.